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Introduction to Pharmacokinetics

Laboratoriumtechniek opleiding - Introduction to Pharmacokinetics
iets voor u?
  • You started working in an environment or drug development of pharmacokinetics.
  • You have a special interest in pharmacokinetics or toxicokinetics.
  • You want to expand your knowledge on these specific subjects.
In het kort
  • niveau Post-mbo
  • duur 3 dagen
  • studiebelasting n.v.t.
  • studiekosten € 1.850,-
  • startdata
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Introduction- to-Pharmacokinetics

Introduction to Pharmacokinetics

Pharmacokinetics (PK) is generally referred to as ‘what the body does to the drug’ versus ‘what the drug does to the body’ (pharmacodynamics [PD]). Pharmacokinetics describes the fate, or time course, of an administered drug within the body. The physiological processes that determine the time course of the drug are Absorption, Distribution, Metabolism and Elimination (ADME). Both the desired effects and undesired effects of a drug are related to the drug levels in the body. The pharmacokinetic properties of a drug determine these levels. Ultimately, the optimal dose and dosing regimen to reach the desired or therapeutic drug levels are determined by means of pharmacokinetics.

This course will focus on the physiochemical properties underlying the pharmacokinetics of a drug, will give insight in the calculation and interpretation of the pharmacokinetic parameters and will also explain the importance and application of pharmacokinetics in preclinical and clinical drug development.

This course is conducted in cooperation with Kinesis Pharma B.V.

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Praktische informatie
    Doelgroep

    Doelgroep

    You are interested in pharmacokinetics (or toxicokinetics), either because you started a career in drug development or in pharmacokinetics, you regularly interact with others working in pharmacokinetics, or simply because you want to broaden your knowledge on this topic.

    Werkvorm

    Werkvorm

    This course will be a mixture of theoretical background, real-life examples and practical exercises.

    Studiebelasting

    Studiebelasting

    This course has a duration of 3 days.

    Studiekosten

    Studiekosten

    The investment for this course will be € 1.850,- (excluding 21 % VAT).

    You will receive the invoice before the start of the course.

    Diploma

    Diploma

    After this course you will receive a document of participation.

    Resultaat

    Resultaat

    Upon completion of this course you will be familiar with the pharmacokinetic concepts and the underlying physiochemical processes. You will be able to effectively interpret pharmacokinetic information and put it into the context of drug development.

    Contact

    Contact

    Heeft u vragen over deze opleiding? Of kunt u advies gebruiken bij het maken van een keuze? Neem dan vrijblijvend contact op met opleidingsmanager John Hageman via jhageman@avansplus.nl of via 076-5258891.

    Programma
    Understanding of biological processes underlying pharmacokinetics

    • Absorption, including passive diffusion and active drug transport
    • Distribution, including tissue distribution and plasma protein binding
    • Metabolism, including enzymatic transformation, inhibition and induction
    • Elimination, including renal excretion
    • Interpreting volume of distribution and clearance

    programma Introduction to Pharmacokinetics day 1
    Cal culation and interpretation of pharmacokinetic parameters

    • Pharmacokinetics after a single IV dose
    • Pharmacokinetics after an extravascular dose
    • Pharmacokinetics after repeated dosing
    • Urinary pharmacokinetic parameters
    • Linear versus non-linear pharmacokinetics

    programma Introduction to Pharmacokinetics day 2
    Pharmacokinetics in practice

    • The role of pharmacokinetics in preclinical and clinical drug development
    • Case study
    • General introduction into pharmacokinetic /pharmacodynamic modeling

    programma Introduction to Pharmacokinetics day 3
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